NASA, SpaceX Dragon to Deliver Heart Studies, More to Space Station

NASA has another cargo shipment en route to the International Space Station following a successful Falcon 9 launch of SpaceX's 27th resupply mission for the agency.

Carrying more than 6,200 pounds of science experiments, crew supplies, and other cargo, the SpaceX Dragon spacecraft was launched to the space station by a Falcon 9 rocket at 8:30 p.m. EDT Tuesday from NASA's Kennedy Space Center in Florida.

The cargo spacecraft is scheduled to autonomously dock with the space station at 7:52 a.m. EDT Thursday, March 16, and remain at the station for about 30 days.

Among the science experiments Dragon is delivering to the space station for NASA and its partners are:

3D Heart Cells, Tissue

The first Cardinal Heart investigation conducted aboard the space station showed that four weeks of microgravity exposure can cause significant changes in heart cell function and gene expression. Researchers concluded that these changes could lead to long-term medical issues. The Cardinal Heart 2.0 experiment builds on these results, using heart organoids, 3D structures made up of all the different types of cells, to test whether clinically approved drugs reduce these microgravity-induced changes in heart cell function. Results could support the development of effective drug combinations to improve the health of astronauts and patients on Earth.

The Engineered Heart Tissues-2 study continues work with 3D cultured cardiac muscle tissue to assess human cardiac function in microgravity. Previous work with 3D cultures in space detected changes at the cellular and tissue level that could provide early indication of the development of cardiac disease. This investigation tests whether new therapies prevent these adverse spaceflight effects from occurring. The model used in this study has potential use in drug development and other applications related to diagnosing and treating cardiac dysfunction on Earth.

Cardinal Heart 2.0 and Engineered Heart Tissues-2 are the final two experiments comprising the National Institutes for Health and International Space Station National Lab's Tissue Chips in Space initiative. Researchers hope to learn more about the impact of microgravity on human health and disease, and translate that understanding to improved human health on Earth.

Student Ball Clamp Monopod Project

NASA's HUNCH (High school students United with NASA to Create Hardware) program enables students to fabricate real-world products for NASA as they apply their science, technology, engineering, and mathematics skills. The HUNCH Ball Clamp Monopod attempts to address astronaut comments on the difficulty of positioning video or still cameras in the middle of a module. The student-manufactured project is composed of an aluminum monopod fitted with a camera shoe and ball clamp that can be attached to a standard space station handrail. The ball clamp serves as a pivoting platform for photography and video.

Liquid Life Support Systems

Because microgravity makes it difficult to control the flow of liquids, the space station has been unable to take advantage of carbon dioxide removal methods that use specialized liquids. Liquid-based carbon dioxide removal systems such as those on submarines offer higher efficiency than other types of systems. The CapiSorb Visible System study demonstrates liquid control using capillary forces, the interaction of a liquid with a solid that can draw a fluid up a narrow tube, which are characteristic of liquids that can absorb carbon dioxide. This is an important consideration for future longer-duration space missions where improved efficiency will support crews over many months or years.

Bacterial Biofilms

Microbial biofilms are combinations of microorganisms that embed themselves in a self-produced slimy matrix. Biofilms are of concern for spaceflight because they can cause damage to equipment, are resistant to cleaning agents, and can harbor microorganisms that might cause infections. The ESA (European Space Agency) Biofilms investigation studies bacterial biofilm formation and antimicrobial properties of different metal surfaces under spaceflight conditions. Antimicrobial surfaces that can inhibit biofilm growth, such as copper and its alloys with and without laser surface treatment, are used in this study. This project provides additional information to help develop suitable antimicrobial surfaces for future spacecraft.

Lifeform Origins, Survival

An investigation from JAXA (Japan Aerospace Exploration Agency) known as Tanpopo-5 could provide insight into whether terrestrial life can survive in space and help scientists understand the key ingredients that sparked life on Earth. The experiment studies the response to space exposure in radiation-resistant microbes, moss spores, and biochemical compounds including amino acids. Amino acids have been detected in extraterrestrial bodies such as meteorites and are possible precursors to life on Earth. Tanpopo-5 follows four earlier experiments which could all inform strategies to protect other planets from contamination by humans and for returning samples from other planets safely to Earth.

These are just a few of the hundreds of investigations currently conducted aboard the orbiting laboratory in the areas of biology and biotechnology, physical sciences, and Earth and space science. Advances in these areas will help keep astronauts healthy during long-duration space travel and demonstrate technologies for future human and robotic exploration beyond low-Earth orbit to the Moon and Mars.

Dragon Docks to Station

SpaceX's Dragon cargo spacecraft autonomously docked to the forward-facing port of the International Space Station's Harmony module on Thursday (March 16) at 7:31 a.m. EDT (1131 GMT) as the two spacecraft were traveling over North Eastern China.

NASA astronaut and Expedition 68 flight engineer Woody Hoburg monitored the docking operations from the station.

Dragon Departs the Space Station

Following commands from ground controllers at SpaceX in Hawthorne, California, Dragon undocked on Saturday (April 15) at 11:05 a.m. EDT (1605 GMT) from the forward port of the International Space Station's Harmony module. At the time of undocking the station was flying over the Indian Ocean.

After re-entering Earth's atmosphere, the spacecraft will make a parachute-assisted splashdown off the coast of Tampa, Florida, in the Gulf of Mexico around 4:58 p.m. EDT (2158 GMT).

Dragon is carrying back to Earth approximately 4,300 pounds (1,950 kilograms) of supplies and scientific experiments designed to take advantage of the space station's microgravity environment. Splashing down off the coast of Florida enables quick transportation of the experiments to NASA's Space Station Processing Facility at the agency's Kennedy Space Center in Florida, allowing researchers to collect data with minimal sample exposure to Earth's gravity.

Some of the scientific investigations that Dragon is carrying include:

• Space tomato harvest: Samples from the Pick-and-Eat Salad-Crop Productivity, Nutritional Value, and Acceptability to Supplement the International Space Station Food System (Veg-05) experiment will be returning to Earth for analysis. Astronauts grew dwarf tomatoes in the station's Veggie miniature greenhouse and performed three harvests at 90, 97, and 104 days. They froze tomatoes, water samples, and swabs of the growth hardware to examine the effects of light quality and fertilizer on fruit production, microbial safety, and nutritional value. The ability to grow plants in space for fresh food and an improved crew living experience is important for future long-duration missions. The hardware could be adapted for use on Earth to provide fresh produce for those without access to gardens and as horticultural therapy for older people and people with disabilities.

• Growing higher quality crystals: Hicari, an investigation from JAXA (Japan Aerospace Exploration Agency), tested a growth method and produced crystals of a silicon-germanium (SiGe) semiconductor using the Japanese Experiment Module-Gradient Heating Furnace (JEM-GHF). This crystal growth method could support development of more efficient solar cells and semiconductor-based electronics. The space-produced crystals are returning to Earth for analysis.

• Analyzing aging arteries: Astronauts can experience accelerated arterial wall stiffening and thickening after six months in space, and a daily session of aerobic exercise alone may not be sufficient to counteract these effects. Vascular Aging, an investigation from CSA (Canadian Space Agency), monitors these changes using artery ultrasounds, blood samples, glucose tolerance tests, and wearable sensors. Results could help identify and assess risk to astronaut cardiovascular health and point to mechanisms for reducing that risk. For the aging population on Earth, understanding the mechanisms behind arterial stiffness could provide insight to guide prevention and treatment. Blood samples collected for the investigation are returning to Earth for analysis.

• Fire safety: Solid Fuel Ignition and Extinction – Growth and Extinction Limit (SoFIE-Gel) studies burning in microgravity, including how fuel temperature affects material flammability. The investigation could improve safety of crew members on future missions by increasing understanding of early fire growth behavior, informing selection of fire-resistant spacecraft cabin materials, validating flammability models, and helping to determine optimal fire suppression techniques. Studying flames in space without the complications of buoyancy also helps improve computer models of combustion for terrestrial applications. Gel samples from the investigation are returning to Earth for further analysis.